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Carbapenem Producing Organisms (CPO) & Candida auris

PICNet  >  Advisories & Policies  >  Carbapenem Producing Organisms (CPO) & Candida auris

The first case of Carbapenem Producing Organism (CPO) in BC was identified in 2008 from a traveler who returned from a CPO-endemic country after undergoing a medical procedure. In the years that followed, there was global and local concern about the rise in CPO and the burden associated with these organisms1. BC monitored CPO and as the number of cases increased, the growing threat of CPO in BC was recognized, and a response was activated. 

PICNet convened the health authorities, BC Centre for Disease Control’s (BCCDC) Public Health Laboratory, and the Ministry of Health. They collectively developed strategies for screening, surveillance and case management for the prevention and control of CPOs in healthcare settings in BC. In alignment to this work, a Ministry of Health Policy Communique was released in July 2014, mandating data collection, reporting, outbreak management strategies and communications processes for acute care settings. 

In December 2016, CPO were designated a reportable condition by the Provincial Health Officer and the provincial mandatory CPO surveillance program was expanded to include CPO isolates in the community. In September 2018, the CPO surveillance protocol was further expanded to include Candida auris (C. auris), a multidrug-resistant fungus first identified in 2009 in Japan and considered an important nosocomial pathogen2. C. auris became reportable in BC in 2018.

Date Description Communiques
Jul 11, 2014 Active surveillance for CPO implemented in BC acute care facilities with requirement for public notification of outbreaks.
Dec 22, 2016 CPO becomes a reportable condition under the Public Health Act. Letter to Provincial Lab Directors... (1076883)
Early 2017 CPO Surveillance protocol modified to include cases identified in outpatients/community, as per reportable condition status. Not applicable
Sep 10, 2018 Candida auris (C. auris) made a reportable condition under the Public Health Act, and CPO surveillance protocol updated to include C. auris. Adding Candida Auris as Reportable Disease (1117568)
  1. CDC. Carbapenem-resistant Enterobacterales (CRE) Infection Control. Enterobacterales (carbapenem-resistance). Published May 16, 2024. Accessed Nov 18, 2024. https://www.cdc.gov/cre/hcp/infection-control/index.html
  2. Candida auris: an emerging antimicrobial-resistant organism with the highest level of concern (thelancet.com)